• Advanced Semen Analysis
  • Advanced Semen Analysis
  • Advanced Semen Analysis
  • Advanced Semen Analysis
  • Advanced Semen Analysis
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Advanced Semen Analysis

DNA fragmentation can be elevated even when standard semen analysis parameters are within reference limits


  • Collect your sample at home and get a more complete clinical picture of your sperm health without a clinic visit. Advanced includes everything in Mate Health’s Comprehensive Semen Analysis, plus DNA Fragmentation Index (DFI) and sperm vitality testing. Every order includes a simplified patient report and physician lab report, plus MateIQ, Mate Health's AI report interpretation tool, which uses peer-reviewed andrology and fertility sources to help you better understand your results. Results are available within 24 hours of laboratory receipt.

    • 22 clinical semen parameters, including advanced diagnostics beyond our Comprehensive Semen Analysis
    • Adds DNA Fragmentation Index (DFI) and vitality (% live sperm)
    • Powered by Mate Health, a CLIA-certified, CAP-accredited high-complexity andrology laboratory
    • WHO 6th Edition semen examination methodology, a global standard
    • Validated Active Cooling specimen transport with FedEx Priority Overnight shipping
    • Not available in New York, Hawaii or Alaska

    Quantity:

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    $440.00 $489.00

    Free shipping, discreet packaging

    HSA/FSA Eligible

    • GMP
      certified

    • Formulated by
      REIs & NDs

    • Third-party
      tested

      Product Details

      The Female Fertility Power Prenatal Pack was developed by fertility doctors to support egg quality, uterine lining, and hormonal balance. Each daily packet contains DHA, essential antioxidants, iron, and prenatals in bioavailable forms at optimal doses. We suggest you take them with food, three hours before or after other medications to maintain the highest efficacy. Feel free to space the pills throughout the day.
      How to Use

      These Early Results Pregnancy Tests are for anyone who wants clear, early answers at home—without waiting until a missed period or heading to a clinic.

      • You’re trying to conceive and want to test as early as five days before your expected period
      • You want over 99% accuracy on the day of your expected period
      • You prefer a simple at-home test with easy-to-read results
      • You want a few tests on hand so you can retest as hCG levels rise

      “One month of these vitamins and could not believe we got a positive test!”

      — Cherie

      Advanced Semen Analysis
      Advanced Semen Analysis
      Advanced Semen Analysis
      Advanced Semen Analysis
      Advanced Semen Analysis

      Which test is right
      for you?

      At-Home Sperm Test Kit

      $99 USD

      At-Home Sperm Test Kit
      Who it's for
      • Couples trying or preparing to conceive who want a quick, at-home test and results
      • Couples who wish to do the testing at home, and not mail-in or in-clinic
      What it includes
      • Everything you need to conduct collection and testing at home
      • Results sent to your smartphone within 20 minutes
      • Live sperm video you can share with your doctor
      What it tests
      • 3 Core Semen Parameters: progressive motility, total motility, concentration
      • 2 Concentration Parameters: motile sperm concentration, progressive motile sperm concentration
      Shop Now - $99

      Comprehensive Semen Analysis

      $249 USD

      Comprehensive Semen Analysis
      Who it's for
      • Couples trying to conceive who want clinically detailed, physician-ready lab results, with sperm collection at home
      • Couples looking for a full motility breakdown (4 classifications), morphology, full sperm counts and functional sperm concentration
      What it includes
      • Everything you need to conduct sample collection at home, plus Active Cooling transport packaging to help preserve your sample in transit
      • Results from a CLIA-certified, CAP-accredited high-complexity andrology laboratory within 24 hours of laboratory receipt
      • Simplified patient report, physician lab report, and microscopy images and videos for physician review
      • Access to MateIQ, Mate Health's AI report interpretation tool, to help you better understand your results
      What it tests
      • All 5 parameters from the At-Home Sperm Test, measured in a clinical laboratory, plus 15 additional parameters, for 20 clinically relevant semen parameters in total:
      • 2 more Core Semen Parameters: volume and morphology
      • 3 more Concentration Parameters: rapid progressive motile sperm concentration, slow progressive motile sperm concentration and functional sperm concentration
      • 5 Counts Per Full Ejaculate Parameters: total sperm count, total motile sperm, progressive motile sperm, functional sperm, morphologically normal sperm
      • 4 Motility Classifications (rapidly progressive, slowly progressive, non-progressive, immotile), plus sperm velocity
      Shop Now - $249

      Advanced Semen Analysis

      $440 USD

      Advanced Semen Analysis
      Who it's for
      • Couples with unexplained infertility, recurrent pregnancy loss and/or preparing for IVF
      • Couples wanting the most complete clinical picture from day one, with sperm collection at home
      What it includes
      • Everything you need to conduct sample collection at home, plus Active Cooling transport packaging to help preserve your sample in transit
      • Results from a CLIA-certified, CAP-accredited high-complexity andrology laboratory within 24 hours of laboratory receipt
      • Simplified patient report, physician lab report, and microscopy images and videos for physician review
      • Access to MateIQ, Mate Health's AI report interpretation tool, to help you better understand your results
      What it tests
      • All 5 parameters from the At-Home Sperm Test, measured in a clinical laboratory, plus 17 additional parameters, for 22 clinically relevant semen parameters in total:
      • 2 Advanced Diagnostics: DNA Fragmentation Index (DFI) and sperm vitality (% live sperm)
      • 2 more Core Semen Parameters: volume and morphology
      • 3 more Concentration Parameters: rapid progressive motile sperm concentration, slow progressive motile sperm concentration and functional sperm concentration
      • 5 Counts Per Full Ejaculate Parameters: total sperm count, total motile sperm, progressive motile sperm, functional sperm, morphologically normal sperm
      • 4 Motility Classifications (rapidly progressive, slowly progressive, non-progressive, immotile), plus sperm velocity
      Shop now - $440

      Say goodbye to bulky bottles

      Save time, money and plastic while getting the best support.

      What other brands offer

      • Bottle clutter and counting pills
      • Ingredient confusion
      • Over $150 a month

      Bird&Be

      • Everything you need in one pack
      • Formulated by fertility doctors
      • Half the price of DIY

      Success Stories

      “I was genuinely amazed by my results during my egg retrieval.”

      My doctors had estimated a maximum of 8 eggs, but I ended up retrieving 14, with 10 fertilized and 6 reaching the blastocyst stage. For anyone familiar with the IVF process, that's an incredible outcome, well above the typical averages.

      — Arielle

      Success Stories

      “After 1.5 months on this prenatal I came pregnant naturally 2 years of trying.”

      I was planning to take these for 3 months prior to starting my first round of IVF. After 1.5 months on this prenatal I became pregnant naturally after trying for 2 years. I do believe my pregnancy has so much to do with these prenatals.

      — Randi

      Success Stories

      “I got pregnant on my very first cycle trying.”

      I had done a lot of research beforehand and wanted something that supported both egg quality and overall reproductive health, and this seemed to have everything I was looking for.

      — Jen

      QUALITY & STANDARDS

      Third-party tested, then tested again

      • Third-Party Tested at Every Stage

        Third-Party Tested at Every Stage

        All Bird&Be formulas and finished products go through strict testing by ISO-accredited third-party labs before they hit shelves.

      • GMP-Certified Facilities

        Our products are made in GMP-certified facilities. That stands for Good Manufacturing Practice, meaning every batch goes through strict quality controls, from ingredient sourcing to final packaging, before it reaches you.

      • Clean Label Project Certified

        Our Clean Label Project certified products went through rigurous testing to ensure they adhere to California's Prop 65 law - some of the strictest standards for supplements on the market.

      • Health Canada Licensed

        Health Canada Licensed

        Health Canada reviews each formula for safety, efficacy, and quality. Every product carries a Natural Product Number (NPN) on the label which serves as proof that all ingredients, dosages and claims are all approved.

      LEARN MORE ABOUT OUR STANDARDS

      Frequently Asked Questions

      What is DNA fragmentation and why does it matter?

      DNA fragmentation measures the percentage of sperm with damaged genetic material. High fragmentation levels are associated with reduced fertility, increased miscarriage risk, failed IVF cycles, and potential developmental issues. DNA damage can exist even when standard sperm parameters such as count, motility, and morphology appear normal, making it an important marker for couples experiencing unexplained infertility or recurrent pregnancy loss.
      What is the difference between comprehensive and advanced semen analysis?

      The advanced semen analysis includes everything in the comprehensive test (20+ parameters such as sperm count, motility, and morphology) plus DNA Fragmentation Index (DFI) testing. DNA fragmentation analysis identifies sperm with damaged genetic material that may impact fertilization success and embryo development—issues that standard semen analysis cannot detect.
      Who should get DNA fragmentation testing?

      DNA fragmentation testing is particularly useful for couples experiencing unexplained infertility despite normal semen parameters, couples with recurrent miscarriages, men undergoing IVF or ICSI procedures, couples with previous failed IVF cycles, men over 40, smokers, or those exposed to environmental toxins or excessive heat.
      Can DNA fragmentation be improved?

      Yes. Unlike genetic mutations, DNA fragmentation is often reversible. Antioxidant supplementation, lifestyle changes such as reducing alcohol and quitting smoking, treating underlying medical conditions, reducing heat exposure, and improving overall health can help reduce fragmentation levels over time. Improvements are typically seen within 2–3 months.
      How is DNA fragmentation measured?

      DNA fragmentation is measured using specialized laboratory testing that evaluates the integrity of sperm DNA. Results are reported as a DNA Fragmentation Index (DFI), representing the percentage of sperm with damaged DNA.
      What is considered a normal DNA fragmentation level?

      DFI below 15% is considered optimal, 15–25% indicates moderate fragmentation that may affect fertility, 25–30% suggests high fragmentation associated with reduced fertility outcomes, and values above 30% are strongly associated with infertility and poor IVF outcomes.
      Can normal sperm count but high DNA fragmentation cause infertility?

      Yes. Some individuals have normal sperm count, motility, and morphology but elevated DNA fragmentation. This can lead to fertilization failure, embryo development issues, implantation failure, or miscarriage even when standard semen analysis appears normal.
      Does DNA fragmentation affect IVF success rates?

      Yes. High sperm DNA fragmentation has been associated with reduced IVF success rates, lower embryo quality, reduced implantation rates, and increased miscarriage risk. In some cases, fertility specialists may recommend techniques such as ICSI or sperm selection to improve outcomes.
      What causes sperm DNA fragmentation?

      Common causes include oxidative stress, smoking, alcohol consumption, obesity, environmental toxins, advanced paternal age, varicocele, high testicular temperature, infections, chronic inflammation, and certain medications or medical treatments.
      Should we pursue IVF if DNA fragmentation is high?

      High DNA fragmentation does not necessarily prevent IVF success, but it may require specialized approaches. A reproductive specialist may recommend lifestyle changes, antioxidant therapy, ICSI with sperm selection techniques, or other treatment options depending on your individual situation.
      How long does advanced semen analysis take?

      Results are typically available within 1–2 business days after the laboratory receives your sample. The advanced analysis includes both standard semen parameters and DNA fragmentation results delivered through a secure online portal.

      Not seeing your question?
      *These statements have not been evaluated by the Food and Drug Administration and Health Canada. This product is not intended to diagnose, treat, cure, or prevent any disease.